Washington Univesity-St. Louis School of Medicine Logo PTSD Biological Measures

(IPRAM)

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What is PTSD

PTSD Biological Measures

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There are many physical changes that may be associated with PTSD:

  • Changes to the shape and activity of the amygdala (a part of the brain)
  • Changes to the shape and activity of the hippocampus (a part of the brain)
  • Chemical changes that affect the way the brain functions
  • Changes to blood flow around and in the brain.
Our Research:

This study is going to examine those physical and chemical changes by the use of magnetic resonance imaging (MRI) and chemical analysis of blood and salivia. The major prediction for PTSD patients exposed to fearful or trauma-related stimuli is that the amygdala (and related structures) will be activated, Prefrontal cortex (PFC) activity will be reduced, and hippocampal activity will be reduced. Fear and stress can physically change the manner in which the brain operates in many different and subtle ways. Our hope is to provide a record of these changes by studying military men and women both before and after deployment.

This information was taken mainly from the National Center for PTSD Fact Sheet by Matthew Friedman, M.D, Ph.D.

For more information on the psychiatric impact of PTSD visit National Center for PTSD Fact Sheet

You may also find additional information by visiting the Uniformed Serviced University of the Health Sciences


Questions or comments? E-mail the webmaster. Last updated: May 5, 2006
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